American Cruise Line offers one-way small ship cruises from Jacksonville to Charleston, South Carolina. The 7-night trips are on the calm Intracoastal Waterway and stop at Amelia Island (Florida), St Simons Island/Jekyll Island (Georgia), Sapelo Island (Georgia), Savannah (Georgia), Hilton Head (South Carolina), and Beaufort (South Carolina) before arriving in Charleston.
Savannah is famous for its beautiful squares and historic style. It's extremely walkable, or you can take a trolley tour. The waterfront is loaded with fun restaurants and shops.
Hilton Head is a well-known oceanfront resort. Hit the beach, play golf, or take a boat tour of the Sea Pines Forest Preserve.
Beaufort is a historic town that attracts many visitors. Tour the neighborhoods and the surrounding Low Country region.
Your cruise ends in Charleston, which was rated #1 city in the USA by Travel + Leisure and Conde Nast Traveler magazine readers. Attractions include a huge historic district, excellent shopping, Fort Sumter, Magnolia Plantation and Middleton Place plantation.